June 8, 2010

Daily Twitter Posting Roundup from @MungosADHD

Here is a roundup of my most recent Twitter posts from @MungosADHD.com:
  • #ADHD New Blog Post: Daily Twitter Posting Roundup from @MungosADHD ow.ly/17E2MR
  • RT @PeterBrownPsy: (6/2010) Thich Nhat Hanh: A Leader In Mindfulness bit.ly/ahuRDL #mindfulness
  • ADD'ing it all up: The Bane of Chaos ow.ly/1V5VC
  • ADHD Medication: $4.2 Billion? Dr. Kenny Handelman ow.ly/1V5Xs
  • #ADHD New Blog Post: Day 4 on Strattera - Subtle Signs of Memory Improvement ow.ly/17EJiF

Cheers,

Mungo

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June 7, 2010

Subtle Signs of Memory Improvement in my Adult ADHD

I'll start this post off with pure excitement! I seem to be managing my constipation with stool softener (Docusate Sodium tablets) and so no return of the signs of the Venusian Tapeworms.

Phew. You can open your eyes now. It's okay. Sit down, have a sip of your milk and relax. Read on:

I think one of the more salient effects of ADHD for me I've noticed over the past couple of months (since I've been paying very close attention and reading a lot about ADHD) or so is feeling like I'm struggling on a journey from day to day, from hour to hour - bewilderingly wandering around a darkened building, moving from room to room, not quite sure where one ends, and where the next one begins. It's like I'm going on blind faith. No preparation, no carrying my calendar with me, no arriving early to make sure I'm ready to go. How can I if I can't even figure out the next location? It is like getting caught in a riptide, just struggling to swim, to get somewhere, anywhere. And constantly frustrated at myself for not preparing, for not getting anywhere, for repeating the same gosh-darned mistakes over and over again. Frustrating myself, and frustrating others - my closest friend, my wife. My friends, my family. It's like one of those anxiety dreams where you end up somewhere where you are supposed to be, but either late or way too early, and without the necessary items or without having prepared or studied for that exam etc...

You might notice the flowing nature of my previous paragraph. That's because this stuff is so familiar to me. I own it, it owns me - it is an easy habit. It reminds me of the etymological source of the word 'habit' - i.e. a habit was clothing monks wore, a piece of clothing they inhabited. A condition, demeanor, appearance, or dress.

Colleagues and friends could look at me and say 'Uhm, you seem confident, you seem certain, you seem experienced and okay' and wonder what all this struggling stuff is about. But - you see - I've learned over the decades to be very camouflaged. My impulsiveness was draped in a clever (or bizarre) sense of humour. My forgetfulness was managed with excuses and frantic catch-ups, and the not-so-occasional Hail Mary pass. My lack of preparation was mitigated by years of learning how to read subtle cues in language and body language so I could bullshit my way through stuff. Unfortunately, bullshitting myself through stuff is the perfect way to erode my self-esteem, my pride, of diminishing the possibilities of developing a sense that I am getting through stuff using honest, healthy, and ethical methods and means.

Today, and over the last couple of days, I found it it easier to decide to hold my tongue and avoid making a crack during a tense meeting to reduce the pressure on a colleague, to distract the attacker, or to fill an uncomfortable moment with humour or to interrupt someone with an impulsive non-sequitur. I'm finding myself more frequently saying 'alright, let's move on' to myself and breaking out of perseverative hyper-focusing.

Today I was imbued with a subtle sense of confidence and optimism. At work I am generally quite busy. Mondays are especially so, I find. I'm going from meeting to meeting, I have one on one meetings with staff members, and work on my own projects and deliverables. I observe my staff with the eyes and ears of a psychologist, and approach work as though I am in university learning new things and also enjoying sharing my knowledge and skills and working with colleagues towards the goal of education and learning about their skills and knowledge. Sharing. I enjoy my job.

But when I'm overwhelmed with all of that toxic stuff, it is hard to enjoy my job, and to be an effective listener, collaborator, educator, sharer.

Well, I don't know if it is the Strattera (in only 4 short days - not all that likely), but I feel like the light has come on in the darkened building a bit for me. I made my way through the day without anxiously consulting my calendar and to-do list and making notes with wide, worried eyes lest I forget things. I still caught myself a few times going places and having forgotten something, but I'm seeing those occasions as being more accidental or explainable due to factors other than working memory deficits.

It's like I just know what to do next. It's the weirdest thing to describe, such a subtle and odd sensation. Not quite confidence, and not quite certainty, but almost like that sense of freedom a kid gets when their bicycle's safety wheel is removed, and they find themselves riding about in zig-zags without falling or faltering.

So - a good day all in all. I know good days come with bad days, and I'll always have to work at this. I'm not being a Pollyanna, or succumbing to the Valence Effect - but I'm okay to feel good and confident today, knowing that tomorrow may bring something different.

Hope y'all had a good day, and are enjoying your evening. My wife is sleeping, recovering from a bad cold and a throat that she says feels like she's swallowed razor-blades (ouch). My little boy is fast asleep hugging his little teddy bear and looking cuter than anything in the whole universe. My dog is snoring gently in his doggie tent a few feet away. And it is time soon for me to go to sleep.

Cheers,

Mungo

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Daily Twitter Posting Roundup from @MungosADHD

Here is a roundup of my most recent Twitter posts from @MungosADHD.com:
  • #ADHD New Blog Post: Day 2 on Strattera - Very Minor Side Effects ow.ly/17DCFo
  • #ADHD New Blog Post: Day 3 on Strattera - Minor Acid Reflux & Expectation Bias ow.ly/17DNhW
  • Melatonin for Sleep: Dr. Kenny Handelman - ow.ly/1UOQz
  • How 'The Hidden Brain' Does The Thinking For Us : NPR ow.ly/1UPfa

Cheers,

Mungo

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June 6, 2010

Minor Acid Reflux & Expectation Bias Now That I'm on Strattera

Today I experienced an brief instance of acid reflux. Nothing I would normally note, except I used to suffer from it, and haven't for a couple of years. So - maybe it was because we had folks over yesterday and I ate foods which didn't agree with me, or maybe it was due to the Strattera.

I have not noticed any significant positive effects of the medication. I say 'I have not' because my expectation is that I won't actually notice anything for at least a week or two or three or four. But there have been several moments today when I've felt clear and my sense of continuity in time (i.e. related to working memory) seems to be more acute, and I find myself remembering things that normally I'm quite sure I'd have forgotten, but I think I will ascribe that to the cognitive bias known as expectation (or Experimenter's) bias.

But those brief moments were counterbalanced by a long period of time this morning where I perseverated and hyperfocused on reading news and couldn't for the life of me get away from my computer.

Had my 10 mg dose at 7:10 PM. To remember, I have an alarm set on my BlackBerry that beeps over and over and over and over again until I am tempted to shred the loathsome beeping device. To wit:



I also have set a calendar event in Google Calendar to send me an alert by e-mail.

Anyway, that's Day 3. No hair loss, no suddenly finding myself in Wisconsin, wondering who I am, and no bed wetting. So far, so good.

Cheers,

Mungo

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June 5, 2010

Very Minor Side Effects of Strattera for Adult ADHD

I woke up in the middle of the night with my bed side light still on, so maybe the Strattera made me fall asleep the moment my head hit the pillow, before the 2 second interval that I normally wait before turning off the light. Or maybe I'd just had a long day.

Today I didn't experience any urinary retention (as in difficulty in 'watering the geraniums' as noted yesterday).

I did experience a slightly shocking moment when I saw blood in my stool (yes, I just wrote that, and you just read that). But I suspect this is simply due to the constipation that Strattera can induce as a side-effect (hey, if you didn't want to read that, then you could have stopped after the previous sentence...). But that was only once, and after a brief flurry of reading medical sites, I've determined it is not something scary like Venusian Tapeworm infestation or something worse. Just a little internal distress.

Now, somewhere between side-effects and positive effects are the 'I wonder where that came from?' effects - for example, my subtle ability to levitate small objects from a distance for example. But that just might be something I've always had, but never noticed before.

I took my 10 mg dose at 7:30 PM. I'm trying to figure out a good time to take it - this is right after the toddler goes to bed. Seems a convenient time.

Anyway - more tomorrow. So far I'm feeling fine, overall.

Cheers,

Mungo

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June 4, 2010

Day 1 on Strattera for Adult ADHD & Why I Have Decided To Change my Family Physician

Yesterday afternoon I went to my family doctor who works about an hour or so away from where I live - in my old hometown. I left a little early in order to make it on time, and dropped by my folks' house to say hello first.

Off I went shortly afterward to my appointment, and after waiting for 30 minutes, he walked into the little room where I was sitting with my notebook and pen.

He asked me how I was doing, and took a seat. I told him that I was feeling pretty good. I had been taking the Clonazepam (an anxiolytic in the same class as Valium and Ativan) instead of the Ativan, and that it was far milder, and that I preferred the longer, gentler effects. I told him that I was planning on seeing a psychologist for counseling and that I was glad to be there to find out the results of the tests I took a couple of weeks back (blood tests and ECG).

He looked a bit flustered, and then slowly went through the blood tests and ECG. He went over each item of the blood tests (and on a few I had to ask him 'so what does that mean?')... the bottom line is that my blood tests seemed to impress him considerably. It was as though I had given him a nice watch for his birthday. He kept grinning and saying how good the results were. My blood pressure was 120/70, better than my last one of 120/80.

He seemed so excited to have a healthy person in his office, I guess. I said that I figured losing over 30 pounds might be contributing to my good results. He didn't say anything, but just closed the folder.

He then said that he would then give me a longer prescription for the Clonazapam as it seems to be working for my anxiety, and 5 minutes after he arrived, he got up to leave.

I fretted my brow and reached down for my notebook and asked him "Uhm, so I imagine you will be giving me a prescription for Strattera as per the recommendations of the assessment and evaluation report - the reason I'm here today - right?"

He frowned and absentmindedly flipped through the folder again. He stopped on a page and squinted at it. Then he asked me in a sort of quiet, doubting sort of way, "So you want a prescription for it?"

At that point my inner voice replied "Yes, you genius. That's why I spent nearly a grand on the evaluation, and spent the last fucking three months going to appointments, and ultimately received an authoritative and bona fide psychiatric diagnosis of ADHD Combined Type after attending long sessions with two eminent and very experienced psychiatrists, one who died right after I initially met with him, and with a clinical psychologist and a psychometrist - each of whom specialize in both child and adult attention deficit hyperactivity disorder. And your obvious due diligence as reflected in your unusually thorough understanding and expression of understanding of the report you hold in your hands only serves to strengthen my opinion that you are only being facetious and that indeed you are completely in control and are exceedingly competent and commanding control of this session with your patient whom you have known for nearly 30 years. No actually I'm just kidding. I'm here because I am fond of the smell of this doctor's office. And I especially like the decor. It was nice to see you, I'll now go on my way and not bother you anymore."

Shortly after my inner voice settled down, I took a deep breath and I actually (in real life) responded, using my managerial tone that I use at work to get stuff done.

I locked my eyes on his and said that my understanding was that the assessment he was holding recommends that I am to be put on Strattera, at an initial dose of 10 mg, once daily, and that I was to be titrated up while he monitored me periodically for side-effects, and until I reached an effective dosage. I said that it was indeed my expectation that this is why I had attended the appointment today, so as to review the test results that he had ordered I take, with the express purpose of ensuring I was healthy enough to be put on Atomoxetine (Strattera). And that Strattera was the recommendation contained within the consultation notes, because my comorbid anxiety precluded or at least weighed against my taking any of the stimulant medications for ADHD. I said that my understanding was that The Canadian Attention Deficit Hyperactivity Disorder Resource Alliance also specifically recommends this regime, and that I might potentially eventually end up - once titration ends - on 40, 60 or more milligrams daily, depending on my ability to tolerate the medication, but more importantly depending on when it began to effectively help me manage my ADHD symptoms. And that I expected that I would be meeting with him periodically until the dosage is working.

He looked puzzled and shuffled the papers around a bit, and then wrote out a prescription for both the Clonazepam and the Strattera and told me that I should come back in two weeks and that we would continue from there.

I thanked him for his time, and wished him a good weekend.

On my drive home I decided that once I have gotten through the titration and initial monitoring, that I will change my family doctor of 30 years to someone more local - in Toronto. I'm done. I used to put up with his chit-chat because I believed that he might be using it as a therapeutic mechanism to monitor my behaviour and interactions. Now I think he just likes to talk about himself. I've always been forgiving of his apparent passiveness, assuming his experience was somehow reflected in his few words, and defended his behaviour with family members who also used his services.

It isn't often that I get pissed off like that but boy oh boy.

So - next steps:

I took my capsule last night before bed. There were no general overall bodily side effects. Certainly I won't see any improvement (if this works) for a few weeks. But this morning a strange thing happened as I was getting ready for work having my morning - well - 'tinkle'.

I will use an analogy so that you will not blush and so that I will not blush. Imagine that you were watering the garden - perhaps the geraniums - with a rubbber water hose. And instead of simply turning the water off at the spigot once you were done, you instead - just prior to when you were ready to finish - suddenly squeezed the hose at the base. And now imagine that the hose itself for some odd reason has sensory nerves that can register pain due to unintended premature constriction before the water had fully run out.

Well, that happened. And not in the analogous world. In the bathroom. Nothing to worry too much about, but it was a weird experience. It has happened a couple of times this morning at work too, as I decided to 'water the geraniums'.

I am going to blog daily (if I can) about my observations. I will try not to dwell on the rubber hose analogy. Really. I will try to observe my behaviours, and will endeavor to be quite dispassionate and scientific about my observations.

Cheers,

Mungo

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June 1, 2010

Oigles, Oiks, Harumph, and Pthhtptphtphtpth

The last week or so has been difficult. At various times I have uttered (under my breath) expletives like oigles, oiks, harumph, and pthhtptphtphtpth. I have also used much stronger language, but I will keep this a family friendly blog and leave it to your imagination.

Work has been especially taxing - we are in the midst of a high visibility technical audit from one of the big audit firms, and I am playing a key role in wrangling up the information that the auditor needs. On top of that several team members have been having rather difficult weeks amongst one another, and on their own. I have been needing to keep on top of this set of situations, plus my own regular work - managing the group and managing my own set of overwhelmesque-flavoured projects.

Correspondingly, my inattentive symptoms have decided to show some attention to me and shake me about like a rag doll. My living space in my office at home is slowly becoming cluttered - like a swamp infested with kudzu vine on radioactive fertilizer. You may remember a scene in one of the Aliens movie where humans have been incorporated into a larger organism and they are moaning and enveloped by some great special-effects slime against a strange wall of warped body parts. I fear this may happen to me if I don't declutter quickly and diligently.

I am trying hard to take into account the mindfulness exercises in "The Mindful Way through Depression - Freeing Yourself from Chronic Unhappiness". Now, I'm not depressed, but the psychiatrist who gave me my diagnosis suggested I look into mindfulness exercises as a way to developing effective coping skills for ADHD.


(Preview this book).

The bottom line is that I feel in the grips of strong perseverative paralysis. At home in the evenings I just stay on the web reading news feeds, drinking no-caffeine, no-sugar Coke, and feel like a zombie. I am an absolute pleasure to be around.

In the background of this is my doctor's appointment scheduled for this Thursday afternoon - where I expect I will finally get a prescription for Strattera. I have had some terrific e-mail feedback (which I'll respond personally to - as soon as I get around to it...) about my previous posts about Strattera. While I didn't question the psychiatrist in great detail about why he prescribed Strattera, I did ask a fair bit about the medication and how it would work for me. Because of my comorbid anxiety (which sounds so wonderfully dark), and because of a close family member diagnosed with a tic disorder, and for a few other reasons, the doctor decided on Strattera. It generally takes 4 to 6 weeks for full effects to kick in (much like the SSRIs have done for me in the past). If there is something ADHD has taught me, paradoxically, it is to be patient. And I can wait for a couple of months, as long as I know I'm doing something to help.

I'm not too worried about side effects that sound like those of SSRIs. Been there, experienced that, expecting that, can cope with that. I figure it is part of the deal.

As I've read (in one of my books), it is possible that the longer time of action the NRIs take versus the stimulants is related to the homeostatis feedback loops of normal neurotransmitter communications between the limbic and the cortical system - the prefrontal cortex where the executive functions mostly reside are re-adjusted, or brought back into harmony by using a Norepinephrine Reuptake Inhibitor (NRI) - and that this simply takes some time:
"A norepinephrine reuptake inhibitor (NRI, NERI) or adrenergic reuptake inhibitor (ARI), is a type of drug which acts as a reuptake inhibitor for the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET). This in turn leads to increased extracellular concentrations of norepinephrine and epinephrine and therefore an increase in adrenergic neurotransmission."
Dr. Kenny Handelman has a page about Strattera where he explains in simple language how Strattera works:

"Strattera selectively blocks the reuptake of norepinephrine (or noradrenaline) in the brain. This, in and of itself, can increase the ability to pay attention and improve hyperactivity. The interesting thing is that Strattera gradually has a downstream effect on the dopamine in the brain, specifically in the frontal lobe. Now, I am throwing around a lot of medical terms very quickly here. Allow me to explain:

The frontal lobe is the ‘command center’ of the brain. This is the area that new brain imaging studies show is most affected in individuals with ADHD. This command center allows people to use their ‘executive functions’, which are the thinking skills which allow for: sustained concentration, impulse control, delayed gratification, etc.

Norepinephrine and Dopamine are called ‘neurotransmitters’. These are little brain chemicals which jump from one nerve cell to the next in the brain to carry a message through the brain.

In individuals with ADHD, research shows that they have ‘under-activity’ of the dopamine and norepinephrine in the frontal lobes.

ADHD medication generally increases the activity of the brain chemicals dopamine and norepinephrine in the frontal lobe, and in so doing, they increase the attention, and decrease hyperactivity and impulsivity (i.e. they increase these ‘executive functions’)."

The publication Canadian ADHD Practice Guidelines from CADDRA contains policies & approaches to treating ADHD. It seems to support Strattera in my case. In fact, my psychiatrist was (before his untimely passing) the chair of this group:

"The Canadian Attention Deficit Hyperactivity Disorder Resource Alliance (CADDRA) is a national independent not-for-profit association whose members are drawn from Family Practice, Pediatrics, Psychiatry and Child Psychiatry. We support individuals with Attention Deficit Hyperactivity Disorder (ADHD) and their families.

The Canadian ADHD Practice Guidelines (CAP-G) were constructed to help Canadian physicians diagnose and treat ADHD. The CAP-G Committee is part of CADDRA and is composed of experts selected to represent different specialties from across Canada based on their contributions to treatment, education and research in the area of ADHD.

These guidelines are unique in that they:

a) have been produced by a multidisciplinary team
b) are specific to Canadian practice
c) include the entire lifespan of this disorder
d) speak to diagnosis and treatment in real life conditions of practice where resources are limited (Section 1)
e) recognize that ADHD is a disorder which will require treatment using a shared care model between specialists and primary care practitioners. For this reason the guidelines stipulate both what can be handled in primary care as well as guidelines for referral to specialists."

Well, I think I've been rambling a little - so I'll boil it down:
  1. Tough week - feeling especially paralyzed and unfocused and unable to take the initiative, despite a few wins (mowing the lawns at home, being quite productive in short spurts at work around this audit process).

  2. Reading about and using Mindfulness exercises to help me move away from ruminative and perseverative thinking and behaviours. This seems to help.

  3. Finally going to the medical appointment where I expect I will get a prescription for Strattera. It seems to have been a long time and I am anxious to get started on it. I want to see focus and attention and motivation return.
Hope you all have a good week, I'll fill in more details once I get through Thursday's appointment!

Cheers,

Mungo

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